RiUP X5 Plus Neo 60mL.

Guideline for product delivery

Please note that this product takes approximately 1 week to 10 days from order to dispatch.

Products.

Hair regrowth agents in androgenetic alopecia.
Contains 51 TP7T of the active ingredient minoxidil, which provides excellent hair regrowth.

In addition to minoxidil, it contains six active ingredients* that provide a cooling sensation and regulate the environment for hair growth on the scalp.
Simply open the cap and press the container against the scalp to measure out a single 1 mL dose.

*Active ingredients.
◆pyridoxine hydrochloride
◆Tocopherol acetate
◆l-menthol
◆ diphenhydramine hydrochloride
◆Glycyrrhetinic acid
◆ Hinokitiol.

Medicines can lead to serious health problems if the dosage and administration is deviated from. Always read the product instructions carefully before use and observe the dosage and administration. Even if the dosage and administration are observed and used correctly, side effects may occur. If any abnormalities are detected, discontinue use immediately and consult a doctor or pharmacist.

Usage notes.

■■ What not to do ■■
Failure to comply may worsen current symptoms or cause side effects.
1. should not be used by the following persons.
(1) People who have experienced allergic reactions to this product or any of its ingredients.
(2) Women. (As the safety of this product in Japanese women has not been confirmed, women should use female products of the RiUP series containing 1% minoxidil.)
(3) Minors (under 20 years of age).
(No experience of domestic use.)
(4) People with alopecia other than alopecia areata (e.g. alopecia areata, alopecia due to thyroid disease, etc.) or with alopecia of unknown cause. (This product is only effective in alopecia areata migrans.)
(5) People with rapid hair loss or hair falling out in patches.
(More likely to be alopecia other than androgenetic alopecia.)
2.Do not use on the following areas.
(1) This product should only be used on the scalp and should not be taken internally.
(May cause a drop in blood pressure, etc.).
(2) Scalp with scars, eczema or inflammation (redness).
(This may aggravate scratches, etc.).
3.When using this product, avoid the use of other hair-growth products and topical products (ointments, liquids, etc.) on the scalp. If these products are used, discontinue use of this product.
(These drugs may affect the absorption of the drug.)

■■Consulting ■■.
1. the following persons should consult a doctor or pharmacist before use
(1) People who have ever experienced allergic symptoms (e.g. rash/redness, itching, rash, etc.) due to medicines or cosmetics.
(2) People with high or low blood pressure.
(This drug may have an effect on blood pressure.)
(3) Persons with heart or kidney disorders.
(This drug may affect the heart and kidneys.)
(4) Swelling.
(Possible increase in swelling.)
(5) People who have no family members or siblings with androgenetic alopecia.
(Genetic factors are thought to play a major role in the development of androgenetic alopecia.)
(6) Older people (65 years and over).
(In general, older people are more likely to develop undesirable symptoms.)
(7) People with the following diagnoses.
Thyroid dysfunction (hypothyroidism, hyperthyroidism).
(Possible hair loss due to thyroid disease.)
2.If any of the following symptoms occur after use, discontinue use immediately and consult a doctor or pharmacist with these instructions as side effects may occur.

Area concerned: skin
Symptoms: rash/redness* on scalp, itching, rash, dandruff, heat at the site of use, etc.

Area involved: psychoneurotic system.
Symptoms: headache, feeling faint, dizziness

Area concerned: cardiovascular system
Symptoms: chest pain, fast heartbeat.

Area involved: metabolic system.
Symptoms: rapid unexplained weight gain, swollen limbs

*:May appear outside the scalp.

3.If, after 6 months of use, there is no improvement in any of the following, discontinue use and consult a doctor or pharmacist with these instructions.
Degree of alopecia condition, development of raw and soft hair, development of hard hair, degree of hair loss (reduction of thin and short hair loss as well as thick hair is an indication of improvement).
(It may be alopecia other than androgenetic alopecia or the hair loss may be due to other causes.)

4.Discontinue use and consult a doctor or pharmacist with these instructions if, even within 6 months of starting use, the hair loss condition worsens or any of the following hair loss symptoms are observed.
Hair loss other than on the head, patchy or rapid hair loss. (This may be alopecia other than androgenetic alopecia or the hair loss may be due to other causes.)

Other Notes.
1. it takes time for hair to grow. Use daily for at least 4 months until the effect becomes visible. (The effectiveness of this product is recognised after 4 months of use.)
2.The degree to which hair grows varies from person to person and this product does not work for everyone.
3.Continued use is required to maintain the effect, which gradually returns to normal when use is discontinued. (This product does not remove the cause of androgenetic alopecia.)

Indications/effects.

Hair regrowth, hair growth and prevention of the progression of alopecia (hair loss) in androgenetic alopecia.

Dosage and administration

Adult males (20 years and older) apply 1 mL twice daily to the scalp where hair loss is present.
The 1 mL dose should be used regardless of the size of the area of hair loss; 1 mL is designed to be sufficient to cover the entire scalp when applied and spread out.
Note that the container is of the type that can measure 1 mL.

How to use the container.
The container body, measuring chamber and nozzle cannot be detached to prevent accidental ingestion.

Container used in 4 steps.

1. remove the cap.
Hold the container body upright and slowly turn the cap to remove it.
Do not remove the cap upside down or at an angle!
(This can cause chemical leakage.)

2. turn the container upside down.
Turn the container upside down so that the black nozzle points straight down and wait for approximately 3 seconds.
(1 mL of chemical solution accumulates in the measuring chamber).
When you turn it upside down slowly, you can see the chemical solution entering the measuring chamber.

3. apply to the scalp
First, press the tip of the container firmly and vertically against the scalp. Then repeat the application with tongs (several dozen times).
A transparent nozzle emerges from the black nozzle.
Apply at 1 cm~2 cm intervals around the area of concern.
(The chemical solution spreads sufficiently to be effective).

4. close the cap.
When the chemical has completely stopped flowing out, tighten the cap tightly.
Tighten the cap until the faces of the cap and container are aligned!
(If the cap is not tightly closed, the chemical will not accumulate in the measuring chamber the next time it is turned upside down.)

.
1.Use of larger or more frequent doses than the prescribed dosage range will not increase the effectiveness of the product. Strictly adhere to the prescribed dosage and administration. (Using more than the prescribed dosage increases the likelihood of side effects with little or no increase in efficacy.)
2.Take care to avoid contact with the eyes.
In case of contact with the eyes, wash immediately with water or lukewarm water.
If symptoms are severe, seek medical attention from an ophthalmologist.
3. Wash off any chemical solution on your hands thoroughly as contact with the eyes or other mucous membranes with chemical solution on your hands may cause irritation.
4. Avoid contact with objects that may dissolve in alcohol or other substances (spectacle frames, synthetic fibres, etc.).
5. Hairdressing and hair setting sprays should be used after using this product.
6.When using hair dyes (hair colour, hair dye, grey hair dye, etc.), use this product after the hair has been completely dyed.

Ingredients/amounts

In 100 mL
Ingredients: minoxidil.
Content: 5.0 g.
Function: Hair regrowth, hair growth and prevention of the progression of hair loss.

Ingredients: pyridoxine hydrochloride.
Amount: 0.05 g.
Function: controls the excessive secretion of sebum, which causes peroxides and dandruff, and keeps the scalp healthy.

Ingredients: tocopherol acetate.
Amount: 0.08 g.
Function:Has an anti-oxidant action on sebum and a blood circulation-promoting action, keeping the scalp healthy.

Ingredients: l-menthol.
Amount: 0.3 g.
Function: relieves itchy scalp and gives a cooling sensation.

Ingredients: diphenhydramine hydrochloride.
Amount: 0.1 g.
Function:Helps reduce scalp itchiness and keeps the scalp healthy.

Ingredients: glycyrrhetinic acid.
Amount: 0.1 g.
Function:Has anti-inflammatory properties and keeps the scalp healthy.

Ingredients: hinokitiol.
Amount: 0.05 g.
Function:- By its bactericidal action, it suppresses the formation of dandruff and keeps the scalp healthy.

Additives: L-arginine, glycine, 1,3-butylene glycol, dibutylhydroxytoluene, phosphoric acid, ethanol.

Storage and handling precautions

1.After use, cap and store in a cool place away from direct sunlight, high temperatures and cold.
2.Keep out of reach of children.
3.To avoid misuse and preserve quality, do not replace the product in other containers.
4. keep away from fire.
5. do not use products past their expiry date.

[For your use].
Depending on the user's hair quality and concentration of application to one area, the hair may become stiff, difficult to comb through, or turn white in parts (crystallisation of ingredients). Wash hair daily, keep scalp clean and use in accordance with the directions for use and dosage.

[How to wash hair properly].
1. rinse hair and scalp briefly with lukewarm water.
2.To reduce friction on the hair when washing, do not apply the shampoo directly to the hair, but lather it well in the palm of your hand.
3.Massage the scalp with your fingers without using your fingernails.
4. rinse the shampoo well. Residual rinsing can cause dandruff and itching.

[Twice daily hair care routine].
RiUP X5 Plus Neo is applied twice daily, 1 mL at a time, to the scalp where hair loss is occurring.
◎ Time of use.
The timing of the twice-daily application varies according to lifestyle, but it is more effective if used at intervals of time, e.g. morning and evening.
It is also recommended that the scalp is as clean as possible.
Create a habit that suits your lifestyle.

[Hair care Q&A].
Q. What is androgenetic alopecia?
A. Gradual, hereditary thinning and hair loss.
It is generally hereditary thinning or hair loss, which progresses slowly over a number of years.
Normally, the hair on the head grows thick and strong over a period of 2-6 years, but in people with androgenetic alopecia the growth period is shortened, resulting in thin, short hair.
In some people, the onset of the disease can start as early as in their 20s.

Q.Can I use it more than twice a day?
A. RiUP X5 Plus Neo is "twice a day", please observe.
Using more than twice a day or using a larger amount at a time does not increase the effectiveness of the product.
Increasing the frequency or applying more applications is unlikely to speed up hair growth and may instead increase the frequency of side effects.
Do not use double the amount next time because you forgot to use it.

Q. Should I wash my hair every day?
A.It is recommended to wash your hair once a day.
The scalp is the foundation of the hair. Days without washing the hair can leave the scalp unclean, hindering hair growth and the absorption of hair regrowth and hair growth products.
Some people try not to wash their hair, saying, "My hair falls out when I wash my hair..." but the hair that falls out when washing is generally hair that has finished growing, and even a slight tug is enough to make it fall out.
For the sake of your hair, it is recommended to wash your hair once a day in the correct way.

Q. Should I have a massage?
A.We recommend that this is done before RiUP X5 Plus Neo application.
Massage is important for improving blood circulation to the scalp. When the blood circulation in the scalp is improved, the nutrients needed for hair production in the blood are distributed to the scalp. It is recommended to continue this habit before applying RiUP X5 Plus Neo.

Q. Can I use hairdressing products?
A. Use RiUP X5 Plus Neo after it has dried.
There is no need to change your daily hair care routine, but to avoid disturbing the absorption of RiUP X5 Plus Neo, use a hairdressing product after RiUP X5 Plus Neo has been applied and after it has dried.

Contact details.

For enquiries about this product, please contact the shop where you bought it or the following

Taisho Pharmaceutical Company Customer 119 Office
3-24-1 Takada, Toshima-ku, Tokyo 170-8633, Japan
Telephone 03-3985-1800
Opening hours 8:30-21:00 (except Saturdays, Sundays and public holidays).

For more information on this product and useful information on hair care, visit the RiUP homepage...

Taisho Pharmaceutical Co.
3-24-1 Takada, Toshima-ku, Tokyo
Customer 119 Office/Telephone 03-3985-1800

Contact details for the Adverse Effects Relief Scheme.
(Pharmaceuticals and Medical Devices Agency
Tel: 0120-149-931 (toll-free).