Class 1 drug] RiUP Regenne 60mL.

Products.

'RiUP Regenne' is a medicinal product for women with minoxidil as the active ingredient.

Medicines can lead to serious health problems if the dosage and administration is deviated from.
Always read the product instructions carefully before use and follow the dosage and administration.
Even if dosage and administration are followed and used correctly, side effects may still occur.
If any abnormalities are detected, discontinue use immediately and consult a doctor or pharmacist.

Usage notes.

■■ What not to do ■■
(Failure to comply may worsen current symptoms or cause side effects.)
1. should not be used by the following persons
(1) People who have experienced allergic reactions to this product or any of its ingredients.
(2) Minors (under 20 years of age).
No experience of domestic use.
(3) Pregnant women or those who appear to be pregnant and those who are breast-feeding.
The safety of its use during pregnancy has not been adequately confirmed.
Minoxidil is also transferred into breast milk.
(4) People with hair loss due to pregnancy or childbirth.
It is more likely to be alopecia areata other than alopecia areata.
(5) People who have hair loss as a result of stopping the use of contraceptive pills.
It is more likely to be alopecia areata other than alopecia areata.
(6) People with alopecia other than androgenetic alopecia (e.g. thyroid disease, rapid weight loss, alopecia areata) or with alopecia of unknown cause.
The drug is only effective in androgenetic alopecia.
(7) People who have hair loss not only on the top of the head but also on the entire head, including the sides and back of the head.
It may be alopecia other than androgenetic alopecia, such as hair loss due to thyroid disease, which is more common in women than in men, or the hair loss may be due to other causes.
(8) People with rapid hair loss or hair falling out in patches.
It is more likely to be alopecia areata other than alopecia areata.
(9) People who have hair loss due to hairstyles that pull strongly from the scalp.
It is more likely to be alopecia areata other than alopecia areata.
(10) Male.
Men should use products from the RiUP series for men.
2. Do not use on the following areas
(1) This product should only be used on the scalp and should not be taken internally.
May cause a drop in blood pressure, etc.
(2) Scalp with scars, eczema or inflammation (redness). May aggravate scars, etc.
3.When using this product, avoid the use of other hair-growth products and topical products (ointments, liquids, etc.) on the scalp. If these are used, discontinue use of this product. These drugs may affect the absorption of this product.

■■Consulting ■■.
1. the following persons should consult a doctor or pharmacist before use
(1) People who have ever experienced allergic symptoms (e.g. rash/redness, itching, rash, etc.) due to medicines or cosmetics.
(2) People with high or low blood pressure. This product may affect blood pressure.
(3) Persons with heart or kidney disorders. This product may affect the heart or kidneys.
(4) Swelling. May increase swelling.
(5) People who have no family members or siblings with androgenetic alopecia. Genetic factors are thought to play a major role in the development of androgenetic alopecia.
(6) Elderly persons (65 years and older). In general, older people are more likely to develop undesirable symptoms.
(7) People with the following diagnoses.
Thyroid dysfunction (hypothyroidism, hyperthyroidism). Possible hair loss due to thyroid disease.
2.If any of the following symptoms occur after use, discontinue use immediately and consult a doctor or pharmacist with these instructions, as side effects may occur

Relevant areas/symptoms.
Skin - Rash/redness on the scalp*, itching, rash, dandruff, heat sensation at the site of use, etc.
Psychoneurological system - headache, feeling faint, dizziness
Cardiovascular - chest pain, fast heartbeat.
Metabolic system - rapid weight gain with no known cause, swollen limbs
*:May appear outside the scalp.

3. If there is no improvement in any of the following after 6 months of use, discontinue use and consult a doctor or pharmacist with these instructions
Degree of hair loss condition, development of raw and soft hair, development of hard hair, and degree of hair loss. (The reduction of thin and short hair loss as well as thick hair is an indication of improvement.)
It may be alopecia other than androgenetic alopecia, such as hair loss due to thyroid disease, which is more common in women than in men, or the hair loss may be due to other causes.

4. Discontinue use and consult a doctor or pharmacist with these instructions if, even within 6 months of starting use, the hair loss condition worsens or the following hair loss is observed
Hair loss not only on the top of the head but also on the entire head, including the temporal and occipital areas, non-head hair loss, patchy hair loss and rapid hair loss.
It may be alopecia other than androgenetic alopecia, such as hair loss due to thyroid disease, which is more common in women than in men, or the hair loss may be due to other causes.

Other Notes.
1. it takes time for hair to grow. Use the product daily for at least 6 months until the effect can be seen. The efficacy of this product is recognised after 6 months of use.
2.The degree to which hair grows varies from person to person and this product does not work for everyone.
3.Continued use is required to maintain efficacy and will gradually return to normal when use is discontinued. This product does not remove the cause of androgenetic alopecia.

Indications/effects.

Hair regrowth, hair growth and prevention of the progression of alopecia (hair loss) in androgenetic alopecia.

Dosage and administration

Adult women (20 years and older) apply 1 mL twice daily to the scalp where hair loss is present.

Use 1 mL at a time, regardless of the size of the area of hair removal.
1 mL is designed as a sufficient amount to cover the entire scalp when applied and spread.
Note that the container is of the type that can measure 1 mL.

How to use the container.

The container body, measuring chamber and nozzle cannot be detached to prevent accidental ingestion.

Container used in 4 steps.

1. open the cap.
Hold the container body upright and slowly turn the cap to open.

◆ If opened upside down or at an angle, the chemical may drip.
◆ Make sure that the black nozzle protrudes from the end of the container.
(If it does not come out, tighten the cap again.)
2. turn the container upside down.
Turn the container upside down so that the black nozzle points straight down and wait for approximately 3 seconds.
(1 mL of chemical solution accumulates in the measuring chamber).
◆ Turn the container upside down slowly to allow the chemical to enter the measuring chamber.
3. apply to the scalp
Press the tip of the container straight and firmly against the scalp.
A transparent nozzle comes out of the black nozzle.
◆Apply the tip of the container (transparent nozzle) to the area of concern and the surrounding area by gently pressing and releasing the tip of the container repeatedly until no more liquid comes out.
◆ 1 mL once a time is effective.
4. close the cap.
Tightly close the cap when the chemical has completely stopped flowing.
◆Cap tightly closed and ready for the next time.
◆ Avoid exposure to sunlight and high temperatures.
◆The chemical may come out more vigorously when applied, depending on temperature changes, such as during hot weather or in areas with high temperatures.

<Attention.
1.Use of larger or more frequent doses than the prescribed dosage range will not increase the effectiveness of the product. Strictly adhere to the prescribed dosage and administration. (Using more than the prescribed dosage increases the likelihood of side effects with little increase in efficacy).
2.Take care to avoid contact with eyes. In case of contact with eyes, wash immediately with water or lukewarm water. If symptoms are severe, seek medical attention from an ophthalmologist.
3. Wash off any chemical solution on your hands thoroughly as contact with the eyes or other mucous membranes with chemical solution on your hands may cause irritation.
4. For people with long hair, push hair out and apply carefully to the scalp to avoid getting the chemical on the hair.
5. Avoid contact with objects that may dissolve in alcohol or other substances (spectacle frames, synthetic fibres, etc.).
6. Hairdressing and hair setting sprays should be used after using this product.
7. When using hair dyes (hair colour, hair dye, grey hair dye, etc.), use this product after the hair has been completely dyed.
8. If you wear false hair or hairpieces, allow this product to dry thoroughly before applying it.

Ingredients/amounts

In 100 mL
Ingredients - Amounts - Functions
Minoxidil - 1.0 g.
... Hair regrowth, hair growth and prevention of the progression of hair loss.

Pantothenyl ethyl ether - 1.0 g.
... Nourishes hair cells and ensures a healthy scalp.

Tocopherol acetate - 0.08 g.
... Prevents the oxidation of sebum and protects the scalp.

l-menthol - 0.3 g.
Helps relieve itchy scalp and gives a cooling sensation.

Additives: 1,3-butylene glycol, citric acid, ethanol, sodium hyaluronate, fragrance-free (immediately after use there is a slight odour of ethanol etc.).

Storage and handling precautions

1.After use, cap and store in a cool place away from direct sunlight, high temperatures and cold.
2.Keep out of reach of children.
3.To avoid misuse and preserve quality, do not replace the product in other containers.
4. keep away from fire.
5. do not use products past their expiry date.

[Other information in the accompanying text].
Hair takes time to grow.
To realise the benefits of RiUP Regenne (hair growth, hair growth and prevention of hair loss progression*), please use the product correctly for at least 6 months, following the dosage and administration.
It is also recommended to continue using the product afterwards to maintain its effectiveness.
*Prevention of hair loss progression:.
Effect on hair loss that has already started, preventing its progression and maintaining the current state.

Effective hair washing for healthy and beautiful hair
1. before washing, lightly brush the scalp and hair to facilitate the removal of dirt.
2.Before applying shampoo, wash hair and scalp with lukewarm water to quickly remove dirt. Do not apply shampoo directly to the head, but first lather well in the palm of the hand.
3.To avoid concentrating the shampoo in one area, apply it to the front 3 areas and the back 2 areas of the scalp. Wash your hair with the tips of your fingers, without pinching. Wash the scalp carefully, as rubbing hair against hair can cause cuticles to peel off.
4. rinse carefully to ensure that no shampoo is left behind. Rinsing residue can cause dandruff and itching.
5.Rinse and condition the hair and work the rinse and conditioner through the hair. Rinse the rinse and conditioner just enough to remove the wet feeling.

Twice-daily hair care routine
RiUP Regenne is applied twice daily, 1 mL at a time, to the area of concern for thinning hair.
◎ Time of use.
The timing of the twice-daily application varies according to lifestyle, but it is more effective if used at intervals of time, e.g. morning and evening.
It is also recommended that the scalp is as clean as possible.
Create a habit that suits your lifestyle.
e.g.) In line with the timing of hair washing ...
When washing hair at night
Morning: wake up → apply RiUP Regenne → dry and then hairdress.
Night: wash hair → massage*1 → take enough water out of hair*2 RiUP Regenne application
→ Dry off and go to bed.
When washing hair in the morning
Morning: wake up → wash hair → massage*1 → get enough water in hair*2 RiUP Regenne application
→ Dry and then hairdressing.
Night: apply RiUP Regenne → dry and go to bed.
*1: Massage should be performed prior to RiUP Regenne application.
*2: Use RiUP Regenne only after hair is thoroughly dry.

Hair care Q&A
Q. How do I know if it works?
A. If you have used the product for six months according to the dosage and administration, please check the following points carefully
Hair loss?
As well as thick hair loss, check for a reduction in thin, short hair loss, which is common in androgenetic alopecia. RiUP Regenne also prevents hair loss that has already started from progressing further. Check for hair loss during washing and hairdressing.
And the ingrown hairs?
Touch the scalp lightly. Check for the feeling of new soft or downy hairs.
How strong is your hair?
Touch your hair. Does the hair feel firmer? Check if the hair has become thicker and firmer.
What is the degree of hair loss?
Check in the mirror. Visually check the condition of your hair.

Q. Under what circumstances should I discontinue use?
A. Discontinue use in the following cases.
◆If no effect is observed after 6 months of use according to the dosage and administration.
◆If the following symptoms are observed after use.
... skin, neuropsychiatric, cardiovascular and metabolic symptoms.
... worsening of the hair loss condition or the development of alopecia other than androgenetic alopecia.
Continued use may lead to further symptoms such as itching, rashes and hair loss.

Q. Can I use hairdressing products?
A.After applying RiUP Regenne, allow it to dry before using.
There is no need to change your daily hair care routine, but to avoid disturbing the absorption of RiUP Regenne, use a hairdressing product after application and after it has dried.

Q. Can I use hair dye or have a perm?
A. If you dye or perm your hair, wash your hair and scalp and rinse off RiUP Regenne before doing so. If you use RiUP Regenne after dyeing or perming your hair, please use it after you have finished dyeing or perming your hair completely.

Q. Can I use hairpieces, wigs or false hair?
A.After applying RiUP Regenne, allow it to dry before using.

Contact details.

If you have any problems Contact us about this product at the shop where you bought it or at
Please contact the following.
Taisho Pharmaceutical Company Customer 119 Office
3-24-1 Takada, Toshima-ku, Tokyo 170-8633, Japan
03-3985-1800
8:30~21:00 (except Saturdays, Sundays and public holidays).